Bernhard Nieswandt Selected Research

Immunoglobulin Fab Fragments

11/2017	CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice.
4/2011	Sustained reperfusion after blockade of glycoprotein-receptor-Ib in focal cerebral ischemia: an MRI study at 17.6 Tesla.
2/2010	Inhibition of platelet GPIb alpha and promotion of melanoma metastasis.
5/2007	Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding.

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Bernhard Nieswandt Research Topics

Disease

88	Thrombosis (Thrombus) 12/2022 - 06/2002
35	Stroke (Strokes) 07/2022 - 03/2006
30	Inflammation (Inflammations) 01/2022 - 02/2006
21	Hemorrhage 01/2021 - 03/2003
18	Ischemic Stroke 01/2022 - 06/2005
13	Infarction (Infarctions) 01/2022 - 05/2007
10	Thrombocytopenia (Thrombopenia) 01/2022 - 03/2003
10	Vascular System Injuries 04/2019 - 01/2003
9	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 10/2021 - 05/2007
9	Myocardial Infarction 11/2020 - 06/2005
8	Brain Ischemia (Cerebral Ischemia) 05/2014 - 03/2006
7	Neoplasms (Cancer) 01/2020 - 02/2010
6	Reperfusion Injury 01/2021 - 04/2007
6	Atherosclerosis 01/2017 - 06/2009
5	Ischemia 11/2019 - 10/2012
5	Brain Infarction 09/2013 - 04/2008
4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 09/2021 - 02/2010
4	Cerebral Infarction 02/2021 - 05/2007
4	Neoplasm Metastasis (Metastasis) 01/2020 - 02/2010
4	Pulmonary Embolism 04/2015 - 07/2006
3	Neuroinflammatory Diseases 09/2021 - 01/2016
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2021 - 05/2015
3	Rupture 01/2017 - 06/2005
3	Atherosclerotic Plaque (Atheroma) 01/2012 - 06/2005
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2005 - 11/2004
2	Infections 04/2021 - 05/2014
2	Pneumonia (Pneumonitis) 01/2018 - 12/2009
2	Cerebral Hemorrhage 01/2017 - 12/2015
2	Hyperalgesia 01/2017 - 07/2014
2	Scott Syndrome 11/2016 - 02/2016
2	Thromboinflammation 11/2016 - 05/2015
2	Body Weight (Weight, Body) 01/2016 - 09/2010

Drug/Important Bio-Agent (IBA)

35	Glycoproteins (Glycoprotein)IBA 12/2022 - 04/2003
33	CollagenIBA 03/2022 - 01/2003
16	IntegrinsIBA 01/2022 - 12/2003
15	Proteins (Proteins, Gene)FDA Link 03/2022 - 02/2010
14	Factor XII (Hageman Factor)IBA 11/2021 - 07/2005
12	Collagen ReceptorsIBA 12/2022 - 11/2004
11	Hemostatics (Antihemorrhagics)IBA 12/2019 - 07/2003
10	FibrinIBA 03/2022 - 06/2005
9	Thrombin FDA Link 01/2022 - 07/2004
8	AntibodiesIBA 01/2020 - 03/2003
8	von Willebrand FactorIBA 01/2019 - 04/2009
6	Platelet Membrane GlycoproteinsIBA 01/2022 - 07/2004
6	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 12/2005
6	Peptide Hydrolases (Proteases)FDA Link 12/2021 - 02/2006
6	platelet membrane glycoprotein VIIBA 10/2021 - 06/2005
6	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 09/2021 - 11/2003
6	Immunoglobulin G (IgG)IBA 02/2021 - 03/2003
6	AntigensIBA 02/2021 - 03/2003
6	CalciumIBA 11/2019 - 07/2008
6	LigandsIBA 01/2019 - 12/2007
5	CytokinesIBA 01/2021 - 12/2009
4	Adenosine Diphosphate (ADP)IBA 07/2022 - 04/2003
4	Thromboplastin (Tissue Factor)IBA 12/2021 - 06/2005
4	C-Type Lectins (C-Type Lectin)IBA 04/2021 - 05/2013
4	Pharmaceutical PreparationsIBA 04/2021 - 08/2011
4	Immunoglobulin Fab FragmentsIBA 11/2017 - 05/2007
4	Monoclonal AntibodiesIBA 04/2016 - 08/2006
4	Phospholipases (Phospholipase)IBA 01/2016 - 12/2005
4	EnzymesIBA 01/2016 - 01/2012
4	von Willebrand factor receptor (VWF receptor)IBA 01/2014 - 12/2005
3	Fibronectins (Fibronectin)IBA 03/2022 - 09/2010
3	Biomarkers (Surrogate Marker)IBA 02/2022 - 01/2014
3	Clopidogrel (Plavix)FDA Link 01/2022 - 01/2009
3	adhesion receptorIBA 02/2021 - 04/2009
3	Therapeutic UsesIBA 02/2021 - 06/2015
3	Fibrinogen (Factor I)FDA Link 01/2019 - 01/2012
3	Antigen-Antibody Complex (Immune Complex)IBA 01/2018 - 01/2014
3	Apolipoproteins E (ApoE)IBA 01/2017 - 09/2010
3	triphenyltetrazoliumIBA 04/2016 - 05/2007
3	PhosphatidylserinesIBA 02/2016 - 07/2004
3	1-dodecylpyridoxal (PLD)IBA 01/2016 - 11/2012
3	Epinephrine (Adrenaline)FDA LinkGeneric 04/2015 - 07/2005
3	phospholipase D1IBA 08/2014 - 01/2010
3	LipidsIBA 09/2013 - 06/2005
3	Protein Isoforms (Isoforms)IBA 09/2013 - 03/2007
3	CoagulantsIBA 07/2013 - 09/2011
3	P-SelectinIBA 02/2010 - 07/2006
3	Integrin alpha2beta1IBA 11/2007 - 04/2003
3	Platelet Glycoprotein GPIIb-IIIa ComplexIBA 07/2006 - 06/2002
2	Actins (F Actin)IBA 12/2022 - 01/2020
2	Laminin (Merosin)IBA 03/2022 - 01/2019
2	ChemokinesIBA 01/2022 - 01/2020
2	GTP-Binding Proteins (G-Protein)IBA 01/2022 - 03/2009
2	Syk KinaseIBA 12/2021 - 01/2021
2	InterleukinsIBA 01/2021 - 05/2014
2	AnticoagulantsIBA 01/2021 - 11/2008
2	Carrier Proteins (Binding Protein)IBA 01/2020 - 10/2012
2	Calcium Channels (Calcium Channel)IBA 11/2019 - 04/2016
2	Glucose (Dextrose)FDA LinkGeneric 11/2019 - 01/2016
2	Serotonin (5 Hydroxytryptamine)IBA 01/2018 - 01/2016
2	ThromboxanesIBA 01/2017 - 01/2014
2	ZymosanIBA 01/2017 - 07/2014
2	Stromal Interaction Molecule 1IBA 04/2016 - 08/2011
2	Human Serum Albumin FDA LinkGeneric 01/2016 - 04/2010
2	Factor XIIa (Coagulation Factor XIIa)IBA 01/2016 - 01/2016

Therapy/Procedure

10	Therapeutics 01/2022 - 11/2004
5	Thrombectomy 01/2022 - 10/2018
2	Ligation 01/2021 - 04/2016